Secondary conditions.
Explore conditions that may be caused or aggravated by a service-connected disability.
Browse connections
143 connections across 47 condition groups
Ankle conditions
3 connectionsPossible secondary conditions
Asthma
2 connectionsBack and lumbar spine
6 connectionsPossible secondary conditions
Bipolar Disorder
1 connectionPossible secondary conditions
Burn Pit / Airborne Hazard Exposure (PACT Act)
1 connectionPossible secondary conditions
Cancer and cancer treatment
3 connectionsPossible secondary conditions
- Chemotherapy-Induced Peripheral Neuropathy (CIPN)From Cancer (Chemotherapy-Treated Malignancy)Strong evidence
- Chronic Fatigue / Cancer-Related FatigueFrom Cancer (Any Service-Connected Malignancy or Treatment)Strong evidence
- Major Depressive Disorder / Anxiety Disorder (Cancer-Related)From Cancer (Any Service-Connected Malignancy)Strong evidence
Every connection we have researched.
143 pairings across 47 starting conditions. Open a condition to read its connections, or use the finder above to search.
Ankle conditions3 connections
Back and lumbar spine6 connections
Bipolar Disorder1 connection
Burn Pit / Airborne Hazard Exposure (PACT Act)1 connection
Cancer and cancer treatment3 connections
Carpal Tunnel Syndrome3 connections
Cervical Spine Degenerative Disc Disease2 connections
Chloracne (Agent Orange Exposure)1 connection
Chronic Kidney Disease (CKD)2 connections
Chronic pain and pain treatment4 connections
Chronic Sinusitis3 connections
COPD3 connections
Coronary Artery Disease / Ischemic Heart Disease4 connections
Depression3 connections
Diabetic Retinopathy1 connection
Fibromyalgia3 connections
Flat feet (pes planus)6 connections
Generalized Anxiety Disorder1 connection
GERD3 connections
Glaucoma (Primary Open-Angle)1 connection
Gulf War Illness (Multi-Symptom Illness)1 connection
Gulf War Illness / Fibromyalgia1 connection
Hearing loss3 connections
Hip conditions4 connections
Hypertension3 connections
Hypothyroidism2 connections
Inflammatory Joint Disease or PTSD (Treated with Long-Term Corticosteroids)1 connection
Inflammatory or Autoimmune Condition (Treated with Corticosteroids)1 connection
Knee conditions7 connections
- Ankle Instability / Ankle ArthritisModerate
- Contralateral Knee Degenerative Joint DiseaseStrong
- Contralateral Knee Pain / OsteoarthritisStrong
- Depression / Anxiety (Chronic Mobility Impairment)Strong
- Hip Pain / Hip Bursitis / Hip ArthritisStrong
- Lumbar Strain / Lumbosacral Spine ConditionStrong
- Obesity / Weight Gain (Mobility Impairment)Moderate
Migraines1 connection
Obesity (Secondary to Service-Connected Mobility Impairment)1 connection
Peripheral Neuropathy4 connections
Plantar Fasciitis3 connections
Prostate cancer2 connections
Psoriasis1 connection
PTSD13 connections
- Alcohol Use Disorder (Substance Abuse)Strong
- Bruxism / Tooth DamageModerate
- Erectile DysfunctionStrong
- Gastroesophageal Reflux Disease (GERD)Strong
- Generalized Anxiety DisorderStrong
- HypertensionStrong
- Irritable Bowel Syndrome (IBS)Strong
- Major Depressive DisorderStrong
- Migraine HeadachesStrong
- Obstructive Sleep ApneaStrong
- Orthostatic Hypotension / SyncopeStrong
- Temporomandibular Joint Disorder (TMJ) / BruxismModerate
- Weight Gain → Obstructive Sleep Apnea (Medication-Induced Pathway)Moderate
Rheumatoid Arthritis1 connection
Service-Connected Condition (Treated with Long-Term NSAIDs)1 connection
Service-Connected Condition (Treated with Long-Term Proton Pump Inhibitors)1 connection
Severe Burn Scars1 connection
Shoulder conditions5 connections
Sleep apnea4 connections
Stroke (Cerebrovascular Accident)2 connections
Tinnitus4 connections
Traumatic brain injury11 connections
- Anosmia (Loss of Smell)Strong
- Chronic Traumatic Encephalopathy (CTE) / Post-Concussive NeurodegenerationEmerging
- Depression (Post-TBI)Strong
- Endocrine Dysfunction / Growth Hormone DeficiencyStrong
- Hypopituitarism / Hormonal Dysfunction (Post-TBI)Moderate
- Migraine Headaches (Post-Traumatic)Strong
- Neurocognitive Disorder / Cognitive ImpairmentStrong
- Post-Traumatic Epilepsy / Seizure DisorderStrong
- Sleep Disorder / Insomnia Disorder (Post-TBI)Strong
- Tinnitus (Post-TBI)Strong
- Visual Processing Disorder / Convergence InsufficiencyStrong
Type 2 diabetes9 connections
- Carpal Tunnel Syndrome (Diabetic)Strong
- Coronary Artery Disease / Ischemic Heart DiseaseStrong
- Diabetic Nephropathy (Chronic Kidney Disease)Strong
- Diabetic Retinopathy / Vision LossStrong
- Erectile Dysfunction (Diabetic)Strong
- Falls and Fractures Secondary to Diabetic NeuropathyStrong
- Gastroparesis (Diabetic)Strong
- Hypertension (Diabetic)Strong
- Peripheral Neuropathy (Diabetic)Strong
Understand your next step.
A listing is a starting point for a conversation with your clinician. A claim depends on your condition, your service connection, and evidence that links them.
Secondary claims, explained
What is a secondary service-connected condition?
A disability may qualify for secondary service connection when evidence shows that an existing service-connected condition caused it or increased its severity beyond natural progression. These are the causation and aggravation paths in 38 CFR § 3.310. Having both conditions does not, by itself, establish the connection.
What evidence can establish the connection?
A nexus is the link between the two conditions. Relevant evidence can include medical records, a reasoned medical opinion, and, in some circumstances, lay evidence. A private nexus letter can help, but is not universally required. An opinion should explain how the evidence in your case supports causation or aggravation, rather than only naming a possible association.
Do I have to pay for a private nexus letter?
VA may arrange a C&P examination or request a medical opinion when needed to decide an initial or Supplemental Claim. You can submit an opinion from a treating or independent clinician, but VA does not require everyone to purchase a private nexus letter. Its duty to assist does not guarantee a favorable opinion or a granted claim.
Does aggravation have to be permanent?
Both causation and aggravation are forms of secondary service connection. Aggravation means an increase in severity attributable to a service-connected condition, beyond natural progression. Permanent worsening is not required under Ward v. Wilkie (2019). Section 3.310(b) also requires medical evidence establishing a baseline level of severity; VA deducts the baseline and any natural progression when determining the compensable increase.
Will a secondary condition get a separate rating?
A separately compensable secondary disability may receive its own evaluation, which VA combines with other ratings under 38 CFR § 4.25. Separate diagnoses do not always mean separate ratings: § 4.14 prohibits compensating the same manifestations more than once, and some body systems have additional rating rules. For aggravation, the compensable increase must account for the baseline severity.
When can a secondary claim’s effective date begin?
An effective date generally depends on when VA received the claim and when entitlement arose, with exceptions. A qualifying intent to file may preserve an earlier claim date if VA receives the completed claim within one year. Review deadlines and continuous pursuit can affect the date; a prior denial does not automatically establish an earlier effective date.
Reading the evidence labels
Strong, Moderate, and Emerging are research categories assigned within this library. They are not VA determinations, promises of service connection, or estimates of your approval chances. Read the supporting research and consider how it applies to your own history. Association between conditions does not, by itself, establish that one caused or aggravated the other.
Go to the source
Read the rules and official guidance behind this page.
Claims guidance checked September 9, 2026. Pairing articles contain AI-assisted research; the date above is not a clinical review of every connection.
